Symptomatic Therapy Trials

1. Characterization of Peripheral Muscle Function in Patients With Non-small-cell Lung Cancer Identifier:              NCT01885754    

This study's status is unknown
Patients with lung cancer are more likely to experience cachexia, a severe debilitating disorder causing fatigue, weight loss, muscle wasting and associated with reduced physical function, increased chemotherapy toxicity and reduced survival. The study will explore muscle function, signaling pathways and its relationship to impaired functional capacity of patients with non-small-cell lung cancer(NSCLC); depending if whether they have cachexic state at diagnosis.
Institut universitaire de cardiologie et de pneumologie de Québec

2. Body Composition Analysis for Patient With Lung Cancer Using Computed Tomography Image Analysis (BAT-SCAN) Identifier:             NCT01887769      

This study's status is unknown
This is a retrospective study extending over a period of 3 years conducted at the Institut universitaire de cardiologie et de pneumologie de Québec (2009-2012)., which aims to analyze body composition of patients with lung cancer at diagnosis using computed tomography (CT-Scan) image analysis.
Centre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Quebec

3. Study of a Tiotropium Inhaler For Shortness of Breath in Advanced Non-Small Cell Lung Cancer (TIDAL) Identifier:             NCT01172925      

This study's status is unknown
The feeling of shortness of breath is very common in lung cancer. It is uncomfortable for patients and upsetting for their family. Although drugs like morphine and oxygen can help some patients feel better, they don't help everybody, and they are not used in patients with early symptoms. More relief is needed for these patients. The investigators are studying a drug called tiotropium, which is used in emphysema. It is an inhaler that opens the airways to allow easier breathing. Every patient will get the drug but also a placebo, in a random (flip of a coin) order. They will get each for 2 weeks. The investigators will see if they feel better with the drug.
Juravinski Cancer Center, Hamilton 

5. Move For Surgery - A Novel Preconditioning Program (MFS) Identifier:             NCT03689634      

This study is active but not recruiting participants
Having major chest surgery imposes great stress on the human body, one that is equivalent to running a marathon. Analogous to training before completing a marathon, the investigator designed Move For Surgery (MFS), a novel preconditioning program that encourages and empowers patients to improve their health prior to surgery. The investigator aims to demonstrate that patients who train with Move For Surgery will have lower respiratory complication rates, will recover better, and will leave the hospital sooner than their counterparts.
St. Joseph’s Healthcare, Hamilton

5. An Open-label Prospective Cohort Trial of Curcumin Plus Tyrosine Kinase Inhibitors (TKI) for EGFR -Mutant Advanced NSCLC (CURCUMIN) Identifier:           NCT02321293    

This study's status is unknown

The purpose of this study is is to assess the safety and tolerability of curcumin in combination with EGFR-TKIs in selected patients with advanced non-resectable mutant EGFR NSCLC.
Peter Brojge Lung Cancer Center, Jewish General Hospital
Montreal, Quebec, H3T 1E2