Adjuvant Trials

            ClinicalTrials.gov Identifier                         NCT02273375        
 
This study is currently active, not recruiting. 
 
The purpose of this study is to find out whether it is better to receive a new drug, MEDI4736, or better to receive no further treatment after surgery (and possibly chemotherapy) for lung cancer.         
 
Alberta
Cross Cancer Institute, Edmonton
Tom Baker Cancer Centre, Calgary

Newfoundland & Labrador
Dr H Bliss Murphy Cancer Centre, St John's
 
Nova Scotia
QE II Health Sciences Centre, Halifax

Ontario
Juravinski Cancer Centre at Hamilton Health Sciences, Hamilton
Cancer Centre of Southeastern Ontario at Kingston, Kingston
Lakeridge Health, Oshawa
Ottawa Hospital Research Institute, Ottawa
Algoma District Cancer Program, Sault Ste Marie
Niagara Health System, St Catherines
Health Sciences North, Sudbury
Thunder Bay Regional Health Science Centre, Thunder Bay 
Mount Sinai Hospital, Toronto, ON
Princess Margaret Hospital, University Health Network, Toronto
 
Quebec
McGill University Oncology Department, Montreal

Saskatchewan
Allan Blair  Cancer Centre, Regina
Saskatoon Cancer Centre, Saskatoon 
 

                     ClinicalTrials.gov Identifier                                NCT03447769  

This study is currently active, not recruiting.

 
The primary purpose of the study is to compare the efficacy and safety of canakinumab versus placebo as adjuvant therapy in adult subjects with stages AJCC/UICC v. 8 II -IIIA and the subset of IIIB (T>5cm N2 disease) completely resected (R0) non-small cell lung cancer (NSCLC).
 
Alberta
Edmonton

New Brunswick 
Moncton

Ontario
Hamilton

Quebec
Montreal 

3. AZD9291 Versus Placebo in Patients with Stage IB-IIIA Non-small Cell Lung Carcinoma, Folowing Complete Tumour Resection With or Without Adjuvant Chemotherapy (ADAURA) 
 
            ClinicalTrials.gov Identifier                         NCT02511106         

This study is active but not currently recruiting. 

A Phase III, Double-blind, Randomized, Placebo-controlled Multi-centre, Study to Assess the Efficacy and Safety of AZD9291 Versus Placebo, in Patients with Epidermal Growth Factor Receptor Mutation Positive Stage IB-IIIA Non-small Cell Lung Carcinoma, Following Complete Tumour Resection With or Without Adjuvant Chemotherapy (ADAURA)

New Brunswick
Moncton

Ontario
Brampton

 
                     ClinicalTrials.gov Identifier                                NCT04966663  

This study is currently recruiting.
 
This is a study to look at whether the presence of circulating tumour DNA (ctDNA) in the blood can help to predict whether giving adjuvant treatment after surgery can decrease the chance of the cancer coming back in people with lung cancer.

Ontario
Princess Margaret Cancer Centre, Toronto, ON